DPPS Filters

When precision retention is critical in the sterile filtration of aqueous liquids, DPPS filters deliver configuration flexibility to meet the unique requirements of your application. You choose the pore sizes of the prefilter and final layer based on bacteria size and load. Save time, improve efficiency and avoid searching through a myriad of preconfigured filters -- configure your own quickly to achieve targeted results.

  • SVPs & LVPs 
  • Diagnostics
  • WFI, Water Purification
  • Cell Culture Media
  • Serum, Plasma
  • Vaccines
  • Biologicals
Features and Benefits

DPPS MediaDPPS Filters are bacteria retention filters consisting of two layers of Polyethersulfone (PES) membrane. The bioburden reduction prefilter and the sterilizing grade final filter each come in several pore sizes to meet unique requirements for your application.


  • Prefilter retains large amounts of bacteria and other particulates which can extend the life of final filter, reduce changeouts, and ultimately lower costs
  • Low binding characteristics, well suited for filtering products with preservatives and protein solutions that can adsorb to media
  • Prefilter pore sizes: 0.10 - 1.2 microns
  • Final layer pore sizes: 0.03 - 0.65 microns
Filtration Area

PPS filtration area-3

Quality Assurance

DPPS filters are 100% integrity tested. They are developed and manufactured under an ISO 9001:2015 certified Quality Management System and designed to be used in cGMP-compliant processes. 

View Data Sheet for further product information

DPPS Filters

DPPS/HT Filters

DPPS Mini-Capsules


DPPS filters are validated using test procedures that comply with ASTM F 838-15(ae1) protocols for the determination of bacterial retention in filters used for liquid filtration. The challenge level is a minimum of 107 organisms per cm2 of filter media. CPF filters have > 7-log removal when challenged with the organisms listed below (0.03μm, 0.10μm and 0.22μm meet the FDA definition of sterilizing grade filters). Validation Guides are available upon request.

  • 0.03μm: Acholeplasma laidlawii 
  • 0.10μm: Brevundimonas diminuta
  • 0.22μm: Brevundimonas diminuta
  • 0.45μm: Serratia marcescens
  • 0.65μm: Saccharomyces cerevisiae
DPPS Cartridges 

Available from 5-40 inches in length with several end connections and O-ring options.  For applications using elevated temperatures,  DPPS/HT Cartridges can be used in processes up to 203°F.  Flow rates shown are for final layers.

DPPS cartridge       Critical Process Filtration black and white capsule with etched logo 

DPPS Capsules

These filters are DPPS cartridges encapsulated in a polypropylene shell to minimize exposure to process fluids. A popular choice for single-use applications and can be disposed of easily. Sizes range from 2-30 inches in length. DPPS Capsules are available pre-sterilized. Flow rates shown are for final layers.

DPPS capsule        Critical process black and white capsule with cutout to show cartridge etched logo 

DPPS Mini-Capsule

Mini-capsules are designed for lab scale testing, process development and small batch production with a filtration area of 500 cm2. DPPS Mini-Capsules are available pre-sterilized. Flow rates shown are for final layers.

DPPS mini     Critical Process black and white mini capsule with etched logo

Why Choose Critical Process Filtration?

Quality & Performance
  • Over 20 years of engineering and manufacturing the finest filters for critical applications. 
  • Compliance with industry standards required for your operation
  • Product optimization to meet your performance goals
  • ISO 9001:2015 certified Quality Management System
  • Appropriately rated clean room environment
  • Proven success in pharmaceutical and bioprocessing applications
Price Advantage

It's simple. Our products are very competitively priced. Learn more

Services & Support
  • Presales evaluations/recommendations by highly experienced Application Engineers 
  • Post sales support and trouble shooting
  • Testing & Analysis services (our site or yours)
  • Validation Services

Made in USA 800   90012015Large-(1)

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