PPC Filters

For absolute bacteria and endotoxin retention.

Applications
  • Water for Injection (WFI)
  • Process Water
 
Features and Benefits

PES AsymmetricPPC is a family of pharmaceutical grade, positively charged Polyethersulfone (PES) sterilizing filters. 

 

  • Removes negatively charged biological contaminants
  • Highest available charge capacity
  • Typically exhibits >3-log removal of endotoxin
  • Double-layer configuration provides higher overall capacity and greater assurance of bacteria and endotoxin removal than the single layer SPC Filter 

 

Filtration Area
PPC filtration area
 
View Data Sheet for further product information:
  • Integrity test specifications
  • Materials of construction
  • Operating parameters
  • Sanitization and sterilization
  • Regulation & compliance

PPC Filters
 
Validation

PPC filters are validated using test procedures that comply with ASTM F 838-15(ae1) protocols for the determination of bacterial retention in filters used for liquid filtration. The challenge level is a minimum of 107 organisms per cm2 of filter media. CPF filters have > 7-log removal when challenged with the organisms listed below (0.03μm, 0.10μm and 0.22μm meet the FDA definition of sterilizing grade filters).

Validation Guides are available upon request.

  • 0.03μm: Acholeplasma laidlawii 
  • 0.10μm: Brevundimonas diminuta
  • 0.22μm: Brevundimonas diminuta
  • 0.45μm: Serratia marcescens
Quality Assurance

PPC filters are 100% integrity tested. CPF filters are developed and manufactured under an ISO 9001:2015 certified Quality Management System and designed to be used in cGMP-compliant processes. 

PPC Cartridges 

Available from 5-40 inches in length with several end connections and O-ring options.  

PPS cartridge        Critical Process Filtration black and white capsule with etched logo 

PPC Capsules

These filters are PPC cartridges encapsulated in a polypropylene shell to minimize exposure to process fluids. A popular choice for single-use applications and can be disposed of easily. Sizes range from 2-30 inches in length. PPC Capsules are available pre-sterilized.

PPS capsule        Critical process black and white capsule with cutout to show cartridge etched logo 

Why Choose Critical Process Filters?
Quality & Performance
  • Over 20 years of engineering and manufacturing the finest filters for critical applications. 
  • Compliance with industry standards required for your operation
  • Product optimization to meet your performance goals
  • ISO 9001:2015 certified Quality Management System
  • Appropriately rated clean room environment
  • Proven success in pharmaceutical and bioprocessing applications
Price Advantage

It's simple. Our products are very competitively priced. Learn more

Services & Support
  • Presales evaluations/recommendations by highly experienced Application Engineers 
  • Post sales support and trouble shooting
  • Testing & Analysis services (our site or yours)
  • Validation Services

Made in USA 800   90012015Large-(1)

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