PPC Sterilizing/Endotoxin Filters

For absolute bacteria and endotoxin retention.

Applications
  • Water for Injection (WFI)
  • Cell Culture Medium
  • Sera/Plasma
  • Buffers
  • Vitamins
  • Process Water
 
Features and Benefits

PES AsymmetricPPC is a family of pharmaceutical grade, positively charged Polyethersulfone (PES) sterilizing filters. 

 

  • Removes negatively charged biological contaminants
  • Highest available charge capacity
  • Typically exhibits >3-log removal of endotoxin
  • Double-layer configuration provides maximum assurance of endotoxin and bacteria retention

 

Filtration Area
PPC filtration area
 
View Data Sheet for further product information:
  • Integrity test specifications
  • Materials of construction
  • Operating parameters
  • Sanitization and sterilization
  • Regulation & compliance

PPC Filters

 
Validation

PPC filters are validated using test procedures that comply with ASTM F 838-15(ae1) protocols for the determination of bacterial retention in filters used for liquid filtration. The challenge level is a minimum of 107 organisms per cm2 of filter media. CPF filters have > 7-log removal when challenged with the organisms listed below (0.03μm, 0.10μm and 0.22μm meet the FDA definition of sterilizing grade filters). Validation Guides are available upon request.

  • 0.03μm: Acholeplasma laidlawii 
  • 0.10μm: Brevundimonas diminuta
  • 0.22μm: Brevundimonas diminuta
  • 0.45μm: Serratia marcescens
Quality Assurance

PPC filters are 100% integrity tested. CPF filters are developed and manufactured under an ISO 9001:2015 certified Quality Management System and designed to be used in cGMP-compliant processes. 

PPC Cartridges 

Available from 5-40 inches in length with several end connections and O-ring options.  

PPS cartridge        Critical Process Filtration black and white capsule with etched logo 

PPC Capsules

These filters are PPC cartridges encapsulated in a polypropylene shell to minimize exposure to process fluids. A popular choice for single-use applications and can be disposed of easily. Sizes range from 2-30 inches in length. PPC Capsules are available pre-sterilized.

PPS capsule        Critical process black and white capsule with cutout to show cartridge etched logo 

Why Choose Critical Process Filters?

Quality & Performance
  • Over 20 years of engineering and manufacturing the finest filters for critical applications. 
  • Compliance with industry standards required for your operation
  • Product optimization to meet your performance goals
  • ISO 9001:2015 certified Quality Management System
  • Appropriately rated clean room environment
  • Proven success in pharmaceutical and bioprocessing applications
FAST and Reliable Delivery
  • Products typically ship within 5 days of order receipt
  • Greater than 98% of products ship as promised
Price Advantage

It's simple. Our products are very competitively priced. Learn more

Services & Support
  • Presales evaluations/recommendations by highly experienced Application Engineers 
  • Post sales support and trouble shooting
  • Testing & Analysis services (our site or yours)
  • Validation Services

Made in USA 800   90012015Large-(1)

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