PTR Filters

Validation

PTR cartridges are validated using test procedures that comply with the intent of BFE aerosol efficiency protocols for the determination of bacterial retention in filters used for air and gas filtration. The challenge level for the 0.22µm filter membrane is 7.5 x 10⁷ organisms per cm² of filter media of Brevundimonas diminuta (ATCC 19146). 

PTR filters are also validated using test procedures that comply with ASTM F 838-15(ae1) protocols for the determination of bacterial retention in filters used for liquid filtration. The challenge level is a minimum of 10⁷ Brevundimonas diminuta organisms per cm² of filter media. CPF filters have > 7-log removal when challenged with the Brevundimonas diminuta (0.22µm meets the FDA definition of sterilizing grade filters). Validation Guides available upon request.

Quality Assurance

PTR filters are 100% integrity tested. CPF filters are developed and manufactured under an ISO 9001:2015 certified Quality Management System and designed to be used in cGMP-compliant processes. 

PTR Cartridges 

Available from 5-40 inches in length with several end connections and O-ring options. For applications using elevated temperatures,  PTR/HT Cartridges can be used in processes up to 221°F. 

PTR Capsules

These filters are PTR cartridges encapsulated in a polypropylene shell to minimize exposure to process fluids. A popular choice for single-use applications and can be disposed of easily. Sizes range from 2-30 inches in length.