PNC Filters

For sterilizing filtration of aqueous and non-aqueous liquids that contain negatively charged contaminants.

  • Process Water
  • Water for Injection (WFI)
Features and Benefits

Nylon 6,6PNC is a family of pharmaceutical grade, positively charged Nylon 6,6 membrane sterilizing filters. 


  • Removes negatively charged biological contaminants
  • Broad chemical compatibility
  • Delivers high flow and throughput
  • Available in 0.10, 0.22, 0.45 and 0.65 µm


Filtration Area
PNC filtration area
View Data Sheet for further product information:
  • Integrity test specifications
  • Materials of construction
  • Operating parameters
  • Sanitization and sterilization
  • Regulation & compliance

PNC filters are validated using test procedures that comply with ASTM F 838-15(ae1) protocols for the determination of bacterial retention in filters used for liquid filtration. The challenge level is a minimum of 107 organisms per cm2 of filter media. CPF filters have > 7-log removal when challenged with the organisms listed below (0.10μm and 0.22μm meet the FDA definition of sterilizing grade filters). 

  • 0.10μm: Brevundimonas diminuta
  • 0.22μm: Brevundimonas diminuta
  • 0.45μm: Serratia marcescens
  • 0.65μm: Saccharomyces cerevisiae
Quality Assurance

PNC filters are 100% integrity tested. CPF filters are developed and manufactured under an ISO 9001:2015 certified Quality Management System and designed to be used in cGMP-compliant processes. 

PNC Cartridges 

Available from 5-40 inches in length with several end connections and O-ring options.  

PNC cartridge        Critical Process Filtration black and white capsule with etched logo 

PNC Capsules

These filters are PNC cartridges encapsulated in a polypropylene shell to minimize exposure to process fluids. A popular choice for single-use applications and can be disposed of easily. Sizes range from 2-30 inches in length. PNC Capsules are available pre-sterilized.

PNC capsule        Critical process black and white capsule with cutout to show cartridge etched logo 

Why Choose Critical Process Filters?

Quality & Performance
  • Over 20 years of engineering and manufacturing the finest filters for critical applications. 
  • Compliance with industry standards required for your operation
  • Product optimization to meet your performance goals
  • ISO 9001:2015 certified Quality Management System
  • Appropriately rated clean room environment
  • Proven success in pharmaceutical and bioprocessing applications
Price Advantage

It's simple. Our products are very competitively priced. Learn more

Services & Support
  • Presales evaluations/recommendations by highly experienced Application Engineers 
  • Post sales support and trouble shooting
  • Testing & Analysis services (our site or yours)
  • Validation Services

Made in USA 800   90012015Large-(1)

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